Why Your Body Weight Doesn’t Predict Your Cannabis Tolerance (Your Endocannabinoid System Does) By Maurice Marshall – Uknowmoe2
Most people assume cannabis tolerance works like alcohol — the bigger the body, the more a person can handle.
Wrong.
Cannabis doesn’t bind to stomach mass or blood volume.
It binds to receptors in your brain.
What Actually Controls Your Cannabis Tolerance
Cannabis interacts with your Endocannabinoid System (ECS) — a natural biological system that manages:
Pain
Appetite
Stress
Sleep cycles
Mood and memory
Your tolerance depends on:
How many cannabinoid receptors you have
How sensitive those receptors are
How often cannabinoids activate them
Size is irrelevant. Receptors are everything.
Factors That Influence Tolerance (Ranked)
Real Factor How It Affects Your High Daily Use Receptors become less responsive Genetics Some people naturally have more receptors Chronic stress Lowers ECS activity Quality of sleep Rest restores receptor sensitivity
“I don’t feel anything when I smoke”
→ Doesn't mean you need more cannabis
→ Means your receptors aren’t responding yet
How To Reset Tolerance (Without Quitting)
Try a microbreak:
Cut your current dose in half for 7–10 days
Add CBD at night — CBD helps receiver sensitivity
Increase hydration and sleep quality
Your receptors reset — your tolerance drops — your budget stretches.
